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Specifications
- Antibody type:Primary
- Antigen name:sirtuin 7
- Clonality:Polyclonal
- Gene ID:Q9NRC8
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:SIRT7
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:0.05 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:SIRT7
- Storage buffer:PBS, 0.05% sodium azide.
- Storage temperature:Short term: 4 °C. Long term: Store at –20 °C. Avoid freeze-thaw cycles.
- Concentration:0.5 mg/mL
- Shipping temperature:4 °C
- Immunogen:A mixture of synthetic peptides corresponding to amino acids 35-51 and 361-377 of human SIRT7.
- Purification:Protein G Column
- Cat. no.:10076-328
Specifications
About this item
SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
- SIRT7 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 2.5 μg/mL.
Protein G Column
PBS, 0.2% gelatin, 0.05% sodium azide.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: SIRT7
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human