Anti-MAD2L1 Rabbit Polyclonal Antibody

Supplier: ProSci
10078-964EA 955.07 CAD
Anti-MAD2L1 Rabbit Polyclonal Antibody
MAD2L1 (also called mitotic spindle assembly checkpoint protein, MAD2A, MAD2-like 1 and HsMAD2) is a component of the mitotic spindle assembly checkpoint monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. MAD2L1 inhibits the activity of the anaphase-promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. This protein has a nuclear localization.

MAD2L1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 ?g/mL.

0.02 M potassium phosphate, 0.15 M NaCl, pH 7.2, 0.01% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: MAD2L1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Human
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