Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription. Western Blot (Ab 1-2 μg/mL for 2hrs at RT) Immunohistology (Formalin/paraffin) (Use Ab at 1-2 μg/mL for 30 min at RT) (Staining of formalin/paraffin tissues REQUIRES digestion of tissue sections with pepsin at 1 mg/mL Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37 deg C) Positive Control Breast carcinoma Cellular Localization Cell membrane/cytoplasmic Recognizes Prolactin Receptor. Species Crossreactivity: Human.
Prolactin Receptor antibody can be used in immunohistochemistry starting at 20 ?g/mL.
Protein G Column
10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide, before the addition of glycerol to 40%
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: PRLR
Clonality: Monoclonal
Clone: [AN4.3]
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
