Anti-TUBB3 Mouse Monoclonal Antibody [clone: AA10]

Supplier: Prosci
10075-418EA 1047.29 CAD
Anti-TUBB3 Mouse Monoclonal Antibody [clone: AA10]
Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)

Protein G purified

100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: Tubb3
Clonality: Monoclonal
Clone: AA10
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG
Reactivity: Mammal
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