Anti-PLXDC1 Mouse Monoclonal Antibody [clone: [197C193]]

10076-664EA 1011.8 CAD
Anti-PLXDC1 Mouse Monoclonal Antibody [clone: [197C193]]
Recently, using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9). TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in the endothelium of colorectal cancer, primary cancers of lung, pancreas, breast, and brain. TEM7 is expressed specifically in endothelium of these cancers, whether primary or metastasis. The other six members of this family (TEM1, 3, 4, 5, 8, and 9) also show similar expression pattern in lung and brain tumors, and liver metastasis. Since most of the genes expressed differentially in tumor endothelium are also expressed during angiogenesis, these newly discovered genes might provide important resources for basic and clinical studies of human angiogenesis.

PLXDC1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 10 ?g/mL.

Protein G Column

PBS, 0.05% BSA, 0.05% sodium azide

Store PLXDC1 antibody at 4 °C or -20 °C. As with all antibodies avoid freeze/thaw cycles.

Type: Primary
Antigen: PLXDC1
Clonality: Monoclonal
Clone: [197C193]
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Gibbon, Gorilla, Human
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