Anti-MECR Rabbit Polyclonal Antibody

Supplier: Prosci

10061-776EA 716.01 CAD
Anti-MECR Rabbit Polyclonal Antibody
MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

MECR antibody can be used for detection of MECR by Western blot at 1 - 2 ?g/mL.

MECR Antibody is affinity chromatography purified via peptide column.

MECR Antibody is supplied in PBS containing 0.02% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: MECR
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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