Anti-BCL3 Rabbit Polyclonal AntibodySupplier: Prosci
10062-310EA 716.01 CAD10062-310
Anti-BCL3 Rabbit Polyclonal Antibody
BCL3 Antibody: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ-B proteins. The expression of this gene can be induced by NF-κ-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 ?g/mL.
BCL3 Antibody is affinity chromatography purified via peptide column.
BCL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.