Anti-VTCN1 Rabbit Polyclonal Antibody

Supplier: Prosci

10062-316EA 716.01 CAD
Anti-VTCN1 Rabbit Polyclonal Antibody
VTCN1 Antibody: T cell immunity plays a critical role in host immune surveillance of tumour cell growth and metastatic spread. VTCN1, also known as B7-H4, is a member of the B7 family of immune regulatory molecules. Expressed primarily on the membrane of lymphoid cells, VTCN1 is an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of VTCN1 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumour cells suppress T cell immunity and facilitate tumour progression. VTCN1 may thus be a useful biomarker for the early detection of ovarian cancer.

VTCN1 antibody can be used for detection of VTCN1 by Western blot at 1 - 2 ?g/mL.

VTCN1 Antibody is affinity chromatography purified via peptide column.

VTCN1 Antibody is supplied in PBS containing 0.02% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: VTCN1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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