Anti-PTGDR2 Rabbit Polyclonal Antibody

Supplier: Prosci

10061-798EA 716.01 CAD
Anti-PTGDR2 Rabbit Polyclonal Antibody
PTGDR2 Antibody: The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.

PTGDR2 antibody can be used for detection of PTGDR2 by Western blot at 0.5 - 1 ?g/mL.

PTGDR2 Antibody is affinity chromatography purified via peptide column.

PTGDR2 Antibody is supplied in PBS containing 0.02% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: PTGDR2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
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