Anti-TRIM33 Rabbit Polyclonal Antibody

Supplier: Prosci

10061-916EA 716.01 CAD
Anti-TRIM33 Rabbit Polyclonal Antibody
TRIM33 Antibody: TRIM24 (TIF1alpha), TRIM28 (TIF1beta), and TRIM33 (TIF1gamma) are three related cofactors belonging to the tripartite motif superfamily that interact with distinct transcription factors. The structure of TRIM33 is similar to TRIM24 and TRIM28, exhibiting multiple domains (RING finger, coiled coil, B boxes, PHD/TTC, and bromodomain). TRIM33 functions in cell differentiation and development, playing a role in differentiation of hematopoietic cells. It interacts with the Smad2/3 transcription factor in hematopoietic, mesenchymal, and epithelial cell types to mediate different transcriptional effects in response to TGF-beta. It acts as an E3 ubiquitin-protein ligase and promotes SMAD4 ubiquitination.

TRIM33 antibody can be used for detection of TRIM33 by Western blot at 1 - 2 ?g/mL.

TRIM33 Antibody is affinity chromatography purified via peptide column.

TRIM33 Antibody is supplied in PBS containing 0.02% sodium azide.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: TRIM33
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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