Anti-TESPA1 Rabbit Polyclonal AntibodySupplier: Prosci
10062-030EA 716.01 CAD10062-030
Anti-TESPA1 Rabbit Polyclonal Antibody
TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus (1,4).
TESPA1 antibody can be used for detection of TESPA1 by Western blot at 1 - 2 ?g/ml. Antibody can also be used for Immunocytochemistry starting at 5 ?g/mL. For immunofluorescence start at 20 ?g/mL.
TESPA1 antibody is affinity chromatography purified via peptide column.
TESPA1 antibody is supplied in PBS containing 0.02% sodium azide.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.