Anti-ADAM23 Chicken Polyclonal Antibody

Supplier: ProSci
10071-796EA 1269.69 CAD
Anti-ADAM23 Chicken Polyclonal Antibody
FUNCTION: May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
SUBUNIT: Ligand for integrin beta-V/gamma-3.
SIMILARITY: Contains 1 peptidase M12B domain.
SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein (Potential). Secreted protein. Isoform Gamma.
TISSUE SPECIFICITY: Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.
DEVELOPMENTAL STAGE: Highly expressed in the fetal brain.
DOMAIN:A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.
SUMMARY: This protein is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is highly expressed in the brain and may function as an integrin ligand in the brain.

ADAM 23 antibody can be used for the detection of ADAM 23 by Western Blot.

Phosphate-Buffered Saline. No preservatives added.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: ADAM23
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Chicken
Reactivity: Human
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