Anti-PSMD1 Chicken Polyclonal Antibody

Supplier: ProSci
XW-8127
10071-642EA 1269.71 CAD
10071-642
Anti-PSMD1 Chicken Polyclonal Antibody
Antibodies
FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
SIMILARITY: Contains 10 PC repeats.
SUMMARY: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 beta subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This protein is the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding.

26S proteasome non-ATPase regulatory subunit 1 antibody can be used for the detection of 26S proteasome non-ATPase regulatory subunit 1 by Western Blot.

Phosphate-Buffered Saline. No preservatives added.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type: Primary
Antigen: PSMD1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype:
Reactivity: Human, Dog, Rat, Bovine, Chicken
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