Human Recombinant LIGHT (from Hi-5 Insect Cells)Supplier: ProSci
10072-896EA 392.66 CAD10072-896
Human Recombinant LIGHT (from Hi-5 Insect Cells)
Proteins and Peptides
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Due to glycosylation LIGHT migrates between 20.0-22.5 kDa by SDS-PAGE under non-reducing conditions.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.