Human Recombinant TIMP2 (from E. coli)Supplier: ProSci
10072-670EA 392.66 CAD10072-670
Human Recombinant TIMP2 (from E. coli)
Proteins and Peptides
TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.