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Anti-E2F1 Rabbit Polyclonal Antibody

Supplier: Proteintech
Transcription factor E2F1 (E2F1), also known as RBBP3, is a transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis.This antibody is a rabbit polyclonal antibody raised against the C-terminal 350 aa sequence of E2F1 protein, specifically recognizes the 47kd human E2F1 protein.

Western Blot: Mouse Brain Tissue, 1:200-1:1000; IHC: Human breast cancer Tissue, 1:20-1:200

Type: Primary
Antigen: E2F1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12171-1-AP 10086-212 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen symbol E2F1
Reactivity Human, Rat, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
Antigen synonyms PRB-binding protein E2F-1, E2F1, RBBP3, RBBP-3, RBAP-1, Retinoblastoma-associated protein 1, Retinoblastoma binding protein 3, Transcription factor E2F1, E2F-1, PBR3
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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