Anti-IA-2/PTPRN Mouse Monoclonal Antibody [clone: 1D3F5]

Supplier: Proteintech
10093-080EA 635.16 CAD
Anti-IA-2/PTPRN Mouse Monoclonal Antibody [clone: 1D3F5]
IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family, which contains a transmembrane region, an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.

Western Blot: Human Brain, 1:200-1:2000; IF: HepG2 Cells, 1:10-1:100; IHC: Human Brain Tissue, 1:20-1:200

Type: Primary
Antigen: IA-2/PTPRN
Clonality: Monoclonal
Clone: 1D3F5
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG3
Reactivity: Human
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