Anti-TLE3 Mouse Monoclonal Antibody [clone: 1D11A8]

Supplier: Proteintech
66083-1-IG
10096-040EA 635.16 CAD
10096-040
Anti-TLE3 Mouse Monoclonal Antibody [clone: 1D11A8]
Antibodies
TLE3, also named as KIAA1547 and ESG3, belongs to the WD repeat Groucho/TLE family. It is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE3 is a member of the transducin-like enhancer of split (TLE) family of proteins that have been implicated in the tumorgenesis and classification of sarcomas. It is a candidate biomarker of response to taxane therapy.

Western Blot:293 Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200

Type: Primary
Antigen: TLE3
Clonality: Monoclonal
Clone: 1D11A8
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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