This protein encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response.
Recommended Dilutions: Western Blot: 1:1000, Flow Cytometry: 1:10-1:50
Type: Primary
Antigen: SLC25A17 (solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse