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Anti-ZFYVE21 Rabbit Polyclonal Antibody

Supplier: Prosci
ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.

Type: Primary
Antigen: ZFYVE21
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: near the N-Terminus
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
20 µg 6935_S 10751-686 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen symbol ZFYVE21
Antigen name Zinc Finger, FYVE Domain Containing 21
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoFluorescence Yes
Antigen synonyms Zinc finger FYVE domain-containing protein 21, ZF21
Epitope near the N-Terminus
Concentration 1 mg/ml
Cross adsorption No
Immunogen ZF21 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZF21.
Purification affinity chromatography purified via peptide column.
Form Liquid
Storage buffer PBS containing 0.02% sodium azide.
Storage temperature ZF21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature -20°C
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