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Anti-FAM193B Rabbit Polyclonal Antibody

Supplier: Prosci
FAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.

Type: Primary
Antigen: FAM193B
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: near the N-Terminus
Host: Rabbit
Isotype: IgG
Reactivity: Human



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Size Supplier No. VWR Catalog Number Unit Price Quantity
20 µg 6941_S 10751-688 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen symbol FAM193B
Antigen name Family With Sequence Similarity 193, Member B
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ImmunoFluorescence Yes
Antigen synonyms FAM193B, Protein FAM193B, KIAA1931, IRIZIO
Epitope near the N-Terminus
Concentration 1 mg/ml
Cross adsorption No
Immunogen FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
Purification affinity chromatography purified via peptide column.
Form Liquid
Storage buffer PBS containing 0.02% sodium azide.
Storage temperature FAM193B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature -20°C
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