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Anti-CENPW Rabbit Polyclonal Antibody

Supplier: Prosci
6943_S
CENPW Antibody: CENPW was initially identified as a gene that was upregulated in multiple cancers, and whose overexpression in mouse fibroblast cells gave rise to distinct cancer-specific phenotypes. It was later found to be a nuclear protein that associated with CENPT, a component of CENPA nucleosome complex in the centromere, and is required for proper kinetochore function. CENPW also specifically interacts with the nucleolar phosphoprotein nucleophosmin, also known as B23 It has been suggested that nucleophosmin functions in the assembly of the kinetochore by interacting with CENPW during interphase. Overexpression of CENPW in the SKOV-3 human ovarian cancer cell line as well as in the zebrafish embryo led to apoptosis, suggesting that high levels of CENPW induces apoptotic cell death.

Type: Primary
Antigen: CENPW
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope: near the N-Terminus
Host: Rabbit
Isotype: IgG
Reactivity:




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
20 µg 6943_S 10751-690 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen symbol CENPW
Antigen name Centromere protein W
Reactivity Rat, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
Antigen synonyms C6orf173, CENP-W, CUG2
Epitope N-Terminal
Concentration 1 mg/ml
Cross adsorption No
Immunogen CENPW antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CENPW.
Purification affinity chromatography purified via peptide column.
Form Liquid
Storage buffer PBS containing 0.02% sodium azide.
Storage temperature CENPW antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature -20°C
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