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Anti-DDX60 Rabbit Polyclonal Antibody

Supplier: Prosci
6945_S
DDX60 Antibody: DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.

Type: Primary
Antigen: DDX60
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
20 µg 6945_S 10751-692 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen symbol DDX60
Antigen name DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Reactivity Human, Rat, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ELISA Yes
ImmunoFluorescence Yes
Antigen synonyms DEAD box protein 60, Probable ATP-dependent RNA helicase DDX60
Concentration 1 mg/ml
Cross adsorption No
Immunogen DDX60 antibody was raised against a 17 amino acid synthetic peptide near the center of human DDX60.
Purification affinity chromatography purified via peptide column.
Form Liquid
Storage buffer PBS containing 0.02% sodium azide.
Storage temperature DDX60 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature -20°C
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