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Anti-SELK Rabbit Polyclonal Antibody

Supplier: Prosci
6975_S
SELK Antibody: SELK is a selenoprotein, containing a selenocysteine residue at its active site. SELK is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex, suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins. SELK is also thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages. When these macrophages are activated through different Toll-like receptors, this cleavage is inhibited

Type: Primary
Antigen: SELK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
20 µg 6975_S 10751-704 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen symbol SELK
Antigen name Selenoprotein K
Reactivity Human, Rat, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ELISA Yes
ImmunoFluorescence Yes
Antigen synonyms HSPC297, HSPC030, SELK, SelK, Selenoprotein K
Concentration 1 mg/ml
Cross adsorption No
Immunogen SELK antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SELK.
Purification affinity chromatography purified via peptide column.
Form Liquid
Storage buffer PBS containing 0.02% sodium azide.
Storage temperature SELK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature -20°C
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