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Anti-CBX4 Rabbit Polyclonal Antibody

Supplier: Prosci
7007_S
CBX4 Antibody: Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.

Type: Primary
Antigen: CBX4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
20 µg 7007_S 10751-726 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen symbol CBX4
Antigen name Chromobox Homolog 4
Reactivity Rat, Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
ELISA Yes
ImmunoFluorescence Yes
Antigen synonyms Pc2, CBX4, PC2, Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, NBP16
Epitope N-Terminal
Concentration 1 mg/ml
Cross adsorption No
Immunogen CBX4 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CBX4.
Purification affinity chromatography purified via peptide column.
Form Liquid
Storage buffer PBS containing 0.02% sodium azide.
Storage temperature CBX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature -20°C
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