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Specifications
- Antibody type:Primary
- Antigen name:PH domain and leucine rich repeat protein phosphatase 2
- Clonality:Polyclonal
- Gene ID:Q6ZVD8
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:PHLPP2
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:PHLPP2
- Storage buffer:PHLPP2 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:156 kDa
- Storage temperature:PHLPP2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:PHLPP2 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human PHLPP2. The immunogen is located within the last 50 amino acids of PHLPP2.
- Tested applications:Immunocytochemistry
- Purification:PHLPP2 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10751-738
Specifications
About this item
PHLPP2 Antibody: PHLPP2 is a member of the serine/threonine phosphatase family, which are important regulators of Akt serine-threonine kinases (AKT1, AKT2, AKT3) and conventional/novel protein kinase C (PKC) isoforms. PHLPP1 and PHLPP2 have a similar domain structure and have been shown to dephosphorylate and inactivate, distinct Akt isoforms, at one of the two critical phosphorylation sites required for activation: Serine473. PHLPP2 dephosphorylates AKT1 and AKT3, whereas PHLPP1 is specific for AKT2 and AKT3. PHLPP1 promotes apoptosis and may act as a tumor suppressor. PHLPP2 associates with and is inhibited by adenylyl cyclase type 6 (AC6), thereby allowing Akt activation.
Type: Primary
Antigen: PHLPP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human