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Anti-CHCHD6 Rabbit Polyclonal Antibody

Supplier: Prosci
CHCHD6 Antibody: CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.

Type: Primary
Antigen: CHCHD6
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope: near the N-Terminus
Host: Rabbit
Isotype: IgG



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Size Supplier No. VWR Catalog Number Unit Price Quantity
20 µg 7133_S 10751-824 Each (20µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen symbol CHCHD6
Antigen name Coiled-coil-helix-coiled-coil-helix Domain Containing 6
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
Western blot Yes
Antigen synonyms Mic25, PPP1R23, CHCM1
Epitope N-Terminal
Concentration 1 mg/ml
Cross adsorption No
Immunogen Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6.
Purification affinity chromatography purified via peptide column.
Form Liquid
Storage buffer PBS containing 0.02% sodium azide.
Storage temperature CHCHD6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Shipping temperature -20°C
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