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Anti-CCND3 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CCND3
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL 12155R-CY5.5 10225-292 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen symbol CCND3
Antigen name Cyclin D3
Reactivity Human, Mouse, Rat
Conjugation Cy5.5®
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen synonyms D3-type cyclin, G1/S-specific cyclin-D3,OTTHUMP00000223415, G1/S-specific cyclin D3
Gene ID 896
Modification phospho-Thr283
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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