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Anti-MAPK6 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: MAPK6
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL 12405R-CY5.5 10225-738 Each (100µl) Retrieving Restricted
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SPECIFICATIONS

Antigen symbol MAPK6
Antigen name Mitogen-Activated Protein Kinase 6
Reactivity Rat, Human, Mouse
Conjugation Cy5.5®
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen synonyms PRKM6, ERK3, HsT17250, p97MAPK
Gene ID 5597
Concentration 1 μg/μl
Cross Adsorption No
Purification Purified by Protein A
Form liquid
Storage Buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature Store at 4°C for 12 months
Shipping Temperature 4°C
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