Anti-ROS1 Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss

BS-2504R-CY5

10340-472EA 1226.35 CAD

10340-472

Anti-ROS1 Rabbit Polyclonal Antibody (Cy5®)

Antibodies

Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ROS1
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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