Anti-CD44 Rabbit Polyclonal Antibody (Biotin)

BS-2507R-BIO
10340-508EA 817.82 CAD
10340-508
Anti-CD44 Rabbit Polyclonal Antibody (Biotin)
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: CD44
Clonality: Polyclonal
Clone: 0
Conjugation: Biotin
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:
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