Anti-GZMA Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss

BS-2578R-CY3

10342-106EA 1226.35 CAD

10342-106

Anti-GZMA Rabbit Polyclonal Antibody (Cy3®)

Antibodies

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: GZMA/Granzyme A
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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