Anti-IL1R1 Rabbit Polyclonal Antibody (Cy5.5®)

BS-2594R-CY5.5
10342-374EA 963.48 CAD
10342-374
Anti-IL1R1 Rabbit Polyclonal Antibody (Cy5.5®)
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: IL1R1
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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