Anti-IL1R2 Rabbit Polyclonal Antibody (Cy7®)

Supplier: Bioss
BS-2595R-CY7
10342-448EA 1057.62 CAD
10342-448
Anti-IL1R2 Rabbit Polyclonal Antibody (Cy7®)
Antibodies
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: IL1R2
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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