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Anti-ETHE1 Rabbit Polyclonal Antibody (Cy3®)

Supplier: Bioss
BS-7610R-CY3
Probably plays an important role in metabolic homeostasis in mitochondria. May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. Suppresses p53-induced apoptosis by preventing nuclear localization of RELA.Involvement in disease:Defects in ETHE1 are a cause of ethylmalonic encephalopathy (EE) . EE is an autosomal recessive disorder characterized by neurodevelopmental delay and regression, recurrent petechiae, acrocyanosis, diarrhea, leading to death in the first decade of life. It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ETHE1
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse




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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL BS-7610R-CY3 10465-750 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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SPECIFICATIONS

Antigen symbol ETHE1
Antigen name Ethylmalonic encephalopathy protein 1
Reactivity Human, Mouse
Conjugation Cy3®
Clonality Polyclonal
Antibody type Primary
Host Rabbit
Isotype IgG
ImmunoChemistry Yes
Antigen synonyms HSCO, Hepatoma subtracted clone one protein
Gene ID 23474
Concentration 1 μg/μl
Cross adsorption No
Purification Purified by Protein A
Form liquid
Storage buffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature Store at -20°C for 12 months
Shipping temperature 4°C
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