Anti-TTC3 Rabbit Polyclonal Antibody

Supplier: Bioss
BS-9147R
10667-992EA 677.18 CAD
10667-992
Anti-TTC3 Rabbit Polyclonal Antibody
E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

Recommended Dilutions: IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: TTC3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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