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Specifications
- Antibody type:Primary
- Antigen name:HomeoDomain-only protein
- Clonality:Polyclonal
- Gene ID:84525
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:HOPX
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:TOTO,OB1,CAMEO,HOD,HOP homeobox,HOP,LAGY,NECC1,homeodomain-only protein,SMAP31
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10488-232
Specifications
About this item
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
Recommended Dilutions: IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: HOPX
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat