Anti-PAR4 Rabbit Polyclonal Antibody

BS-9511R
10489-500EA 407.07 CAD
10489-500
Anti-PAR4 Rabbit Polyclonal Antibody
Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

Recommended Dilutions: Western Blot: 1:100-1000; Flow Cytometry: 1:20-100; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: PAR4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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