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Anti-BLNK Rabbit Polyclonal Antibody
Anti-BLNK Rabbit Polyclonal Antibody
Catalog #: 10494-504
Supplier:  Bioss
Anti-BLNK Rabbit Polyclonal Antibody
Catalog #: 10494-504
Supplier:  Bioss
Price
982,68 $
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Unit of Measure Each (100µl)
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Specifications

  • Antibody type:
    Primary
  • Antigen name:
    B-cell linker
  • Clonality:
    Polyclonal
  • Gene ID:
    29760
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Antigen symbol:
    BLNK
  • Conjugation:
    Unconjugated
  • ImmunoChemistry:
    Yes
  • Western blot:
    Yes
  • Cross adsorption:
    No
  • Form:
    liquid
  • Antigen synonyms:
    Src homology 2 domain-containing leukocyte protein of 65 kDa,
    B-cell adapter containing a Src homology 2 domain protein,
    B cell adaptor containing SH2 domain,
    B cell linker protein,
    cytoplasmic adapter protein,
    SLP-65,
    B-cell activation,
    LY57,
    AGM4,
    B-cell adapter containing a SH2 domain protein,
    BLNK-S,
    bca,
    B-cell linker protein,
    SLP65,
    BASH,
    Src homology [SH2] domain-containing leukocyte protein of 65 kD
  • Modification:
    Tyr84
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
  • Storage temperature:
    Store at –20 °C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping temperature:
    4°C
  • Purification:
    Purified by Protein A
  • Cat. no.:
    10494-504

Specifications

About this item

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: BLNK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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