Human Recombinant PDGF-AB (from E. coli)

Supplier: PeproTech

100-00AB-2UG 100-00AB-500UG 100-00AB-10UG 100-00AB-100UG 100-00AB-250UG 100-00AB-1MG
10770-582EA 150.18 CAD
10770-582 10770-602 10770-584 10770-586 10770-600 10770-604
Human Recombinant PDGF-AB (from E. coli)
Proteins and Peptides
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-AB is a 26.4 kDa disulfide-linked dimer, consisting of one α chain and one β chain (234 total amino acids).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR