Human Recombinant FGF-23 (from E. coli)Supplier: PeproTech
100-52-20UG 100-52-100UG 100-52-1MG 100-52-5UG 100-52-250UG 100-52-500UG
10772-248EA 375.23 CAD10772-248 10772-250 10772-256 10772-246 10772-252 10772-254
Human Recombinant FGF-23 (from E. coli)
Proteins and Peptides
The FGF family plays a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-23, FGF-21 and FGF-19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF-23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF-23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1. Recombinant Human FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.