Human;Mouse;Rat Recombinant GDF-11 (from E. coli)Supplier: PeproTech
120-11-100UG 120-11-1MG 120-11-500UG 120-11-250UG 120-11-20UG 120-11-5UG
10772-472EA 1500.95 CAD10772-472 10772-478 10772-476 10772-474 10772-470 10772-468
Human;Mouse;Rat Recombinant GDF-11 (from E. coli)
Proteins and Peptides
GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves the arrest of the progenitor cell cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggest that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant Human/Murine/Rat GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8, sharing 90% amino acid sequence identity.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.