Human;Mouse;Rat Recombinant Activin A (from E. coli)

Supplier: PeproTech

120-14E-1MG 120-14E-500UG 120-14E-10UG 120-14E-250UG 120-14E-50UG 120-14E-2UG 120-14E-100UG
10772-530EA 7319.91 CAD
10772-530 10772-528 10772-520 10772-526 10772-522 10772-518 10772-524
Human;Mouse;Rat Recombinant Activin A (from E. coli)
Proteins and Peptides
Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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