Human Recombinant CYR61 (from E. coli)Supplier: PeproTech
120-25-5UG 120-25-500UG 120-25-250UG 120-25-20UG 120-25-100UG 120-25-1MG
10772-624EA 150.18 CAD10772-624 10772-632 10772-630 10772-626 10772-628 10772-634
Human Recombinant CYR61 (from E. coli)
Proteins and Peptides
CYR61 is a member of the CCN family of secreted cysteine-rich regulatory proteins. CYR61 induces angiogenesis by stimulating the proliferation, migration, and adhesion of endothelial cells. Cell migration and adhesion are mediated through binding to specific cell surface integrins and to heparin sulfate proteoglycans. Increased expression of CYR61 is associated with several types of cancer, and correlates with the progression and estrogen independence of human breast cancers. Recombinant Human CYR61 is a 39.4 kDa protein containing 357 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the Thrombospondin type-I (TSP type-1) domain, and a C-terminal cysteine knot-like domain (CTCK).
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.