Human Recombinant sFRP-1 (from HeLa cells)Supplier: PeproTech
120-29-100UG 120-29-20UG 120-29-500UG 120-29-5UG 120-29-250UG 120-29-1MG
10772-662EA 1464.32 CAD10772-662 10772-660 10772-666 10772-658 10772-664 10772-668
Human Recombinant sFRP-1 (from HeLa cells)
Proteins and Peptides
Secreted Frizzled Related Proteins (sFRPs) modulate WNT signaling by binding directly to WNT proteins in a manner that affects their receptor binding and signaling capabilities. sFRP-1 is a widely distributed protein that can bind directly to WNT1, WNT2, and possibly other WNT proteins, and generally exerts anti-proliferative effects consistent with activity as a WNT antagonist. It also inhibits apoptosis, and has been found to be down-regulated in many solid tumors, but up-regulated in uterine leiomyomas. Recombinant Human sFRP-1 is a glycosylated 283 amino acid protein containing a cysteine-rich Frizzled homologous domain. The calculated molecular weight of Recombinant Human sFRP-1 is 32.5 kDa.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.