Human Recombinant TIGAR (from E. coli)Supplier: PeproTech
150-14-25UG 150-14-500UG 150-14-1MG 150-14-100UG 150-14-250UG 150-14-5UG
10772-836EA 375.24 CAD10772-836 10772-842 10772-844 10772-838 10772-840 10772-834
Human Recombinant TIGAR (from E. coli)
Proteins and Peptides
TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant Human TIGAR expressed in
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.