Human Recombinant TIGAR-TAT (from E. coli)Supplier: PeproTech
150-14T-5UG 150-14T-100UG 150-14T-1MG 150-14T-25UG 150-14T-250UG 150-14T-500UG
10772-846EA 150.18 CAD10772-846 10772-850 10772-856 10772-848 10772-852 10772-854
Human Recombinant TIGAR-TAT (from E. coli)
Proteins and Peptides
TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other intracellular proteins into primary, as well as transformed, cells. Recombinant Human TIGAR-TAT expressed in
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.