Human Recombinant E-Selectin (from CHO cells)Supplier: PeproTech
150-15-100UG 150-15-250UG 150-15-10UG 150-15-1MG 150-15-50UG 150-15-500UG
10772-862EA 563.19 CAD10772-862 10772-864 10772-858 10772-868 10772-860 10772-866
Human Recombinant E-Selectin (from CHO cells)
Proteins and Peptides
Selectins are a family of calcium-dependent type 1 transmembrane proteins. Endothelial (E)-selectin is a heavily glycosylated transmembrane protein expressed by activated endothelial cells in microvascular linings. E-selectin, along with P-selectin and L-selectin, initiate recruitment of circulating leukocytes from blood to sites of inflammation in the vascular lining through interaction with specific cell surface-associated carbohydrate determinants. E-selectin consists of an N-terminal type 1 lectin domain, an EGF-like domain, 6 sushi (CCP/SCR) domains, a transmembrane sequence, and a short cytoplasmic domain. Recombinant Human E-selectin is a 58.6 kDa protein containing 535 amino acid residues, corresponding to the extracellular portion of the full length protein. Due to glycosylation, E-selectin migrates at an apparent molecular weight of approximately 65-85 kDa by SDS-PAGE analysis under reducing conditions.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.