Human Recombinant IL-12P80 (from (BTI-Tn-5B1-4) Hi-5 Insect cells)

Supplier: PeproTech

20012P80H500UG 20012P80H10UG 200-12P80H-1MG 20012P80H100UG 200-12P80H-2UG 20012P80H250UG
10773-044EA 8781.33 CAD
10773-044 10773-038 10773-046 10773-040 10773-036 10773-042
Human Recombinant IL-12P80 (from (BTI-Tn-5B1-4) Hi-5 Insect cells)
Proteins and Peptides
IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicates that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or it can form the homodimer designated IL-12 p80. Elevated levels of IL-12 p80 correlate to macrophage recruitment and increased inflammation in asthma and respiratory viral infection models. Recombinant Human IL-12 p80 is an 80.0 kDa disulfide linked homodimer consisting of two p40 chains of IL-12.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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