Human Recombinant MIP-1beta (from E. coli)

Supplier: PeproTech

300-09-1MG 300-09-250UG 300-09-100UG 300-09-50UG 300-09-500UG
10773-514EA 5630.72 CAD
10773-514 10773-510 10773-508 10773-506 10773-512
Human Recombinant MIP-1beta (from E. coli)
Proteins and Peptides
Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens, by regulating the trafficking, and activation state, of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1α and MIP-1β exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes, and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant Human MIP-1β (CCL4) is a 7.6 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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